Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2006-03-28
2006-03-28
Parsa, J. (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C562S433000, C562S553000
Reexamination Certificate
active
07019161
ABSTRACT:
The present invention relates to novel processes for the preparation of optically active 3-aminocarboxylic acids and their esters, in particular processes for the preparation of optically active compounds of the formula IA or IBas free bases or as acid addition salts thereof, in which the radicals are as defined in the description; in particular using the catalytic hydrogenation of olefinic precursors in the presence of platinum on alumina as a catalyst and the removal of chiral auxiliary groups from salt precursors; and novel process sections in the route for their synthesis, and processes for the preparation of biologically, in particular pharmacologically, active compounds, which comprise the novel processes.
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Cimarelli et al, (2001), Synthetic Communications, 31(19) pp. 2943-2953.
Cimarelli et al, (1996) Journal of Organic Chemistry, 61(16), pp. 5557-5563.
Furukawa et al, Chemical and Pharmaceutical Bulletin (1979) pp. 2223-2226.
Bartoli et al, Journal of Organic Chemistry (1994) 59(18, pp. 5328-5335.
Burkhardt Stephan
Kirner Hans Jörg
Schöning Kai-Uwe
Studer Martin
Ciba Specialty Chemicals Corporation
Mansfield Kevin T.
Parsa J.
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