Processes for spray drying hydrophobic drugs in organic solvent

Details Processes for spray drying hydrophobic drugs in organic solvent Processes for spray drying hydrophobic drugs in organic solvent

1997-12-29

1999-11-02

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424470, 424461, 424 45, A61K 914

Patent

active

059765747

ABSTRACT:
Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions or suspensions of the components and spray drying them simultaneously in a spray drier. The hydrophobic component may be dissolved in an organic solvent and the hydrophilic component suspended therein. The method provides dry powders having relatively uniform characteristics.

REFERENCES:
patent: 4486435 (1984-12-01), Schmidt et al.
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4590206 (1986-05-01), Forrester et al.
patent: 4670419 (1987-06-01), Uda et al.
patent: 4722941 (1988-02-01), Eckert et al.
patent: 4999189 (1991-03-01), Kogan et al.
patent: 5000888 (1991-03-01), Kilbride, Jr. et al.
patent: 5026550 (1991-06-01), Aeschbach et al.
patent: 5260306 (1993-11-01), Boardman et al.
patent: 5376386 (1994-12-01), Ganderton et al.
patent: 5510118 (1996-04-01), Bosch et al.
patent: 5518187 (1996-05-01), Bruno et al.
patent: 5534270 (1996-07-01), De Castro
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101884. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101882. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7242568. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 8067666. One page total.
Mumenthaler et al. "Feasibility study on spray-drying protein pharmaceuticals: Recombinant human growth hormone and tissue-type plasminogen activator" Pharm. Res. (1994) 11(1):12-20.
Bloch et al., "Dispersions of hydrochlorothiazide and chlorthalidone in pentaerythritol" Pharm. Acta Helv. (1983) 58(1):14-22. An English abstract is also enclosed herewith.
Dialog.RTM. Abstract of German Patent Publication No. DE 2209477. One page total.
Dialog.RTM. Abstract of French Patent Publication No. FR. 2594693 One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 4036233. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101881. One page total.
Dialog.RTM. Abstract of Japanese Patent Publication No. JP 7101883. One page total.

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