Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1988-11-04
1991-04-09
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514919, A01N 3718
Patent
active
050065629
ABSTRACT:
N-lower alkyl neoalkanamides (N-lower alkyl trialkylacetamides of certain types) of 1 to 4 carbon atoms in the lower alkyl thereof and of 5 to 14 carbon atoms in the neoalkanoyl (or trialkylacetyl) group, e.g., N-methyl- and N-ethyl neodecanamides and N-methyl and N-ethyl neotridecanamides, are new componds, secondary amides which have insect repellent properties, being especially effective against cockroaches, e.g., the German cockroach. However, they are also useful as repellents for other insects, including American cockroaches, mosquitoes, flies, fleas, ants, and lice. Additionally, they may repel arachnids, such as spiders, ticks and mites. The new neoalkanamides may be synthesized easily, as by reacting a primary lower alkyl amine with a neoalkanoyl halide, e.g. by reacting methyl amine or ethyl amine with neodecanoyl chloride.
The most effective of the described amides for insect repellency are normally liquid and are sufficiently volatile to be detectable in air by insects. They have been found to be of long lasting effectiveness, with significant and measurable insect repellency being obtainable for as long as two weeks after application.
REFERENCES:
patent: 4153679 (1979-05-01), Rowsell et al.
patent: 4497715 (1985-02-01), Bauman
patent: 4682982 (1987-07-01), Steltenkamp et al.
patent: 4804683 (1989-02-01), Steltenkamp
Colgate-Palmolive Co.
Grill Murray M.
Lieberman Bernard
Schenkman Leonard
Sullivan Robert C.
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