Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1994-06-06
1997-03-11
Rories, Charles C. P.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
800205, 800250, 800255, 47 58, 4353201, 435 697, 435141, 435183, 435189, 435195, 536 234, 536 237, C12P 762, A01H 500, C12N 1531, C12N 1587
Patent
active
056100418
ABSTRACT:
The present invention relates to a process for producing poly-D-(-)-3-hydroxybutyric acid (PHB) and related polyhydroxyalkanoates (PHA) in the plastids of plants. The production of PHB is accomplished by genetically transforming plants with modified genes from microorganisms. The genes encode the enzymes required to synthesize PHB from acetyl-CoA or related metabolites and are fused with additional plant sequences for targeting the enzymes to the plastid.
REFERENCES:
patent: 5229279 (1993-07-01), Peoples et al.
patent: 5245023 (1993-09-01), Peoples et al.
patent: 5250430 (1993-10-01), Peoples et al.
Anderson, A.J. and Dawes, E.A., Microbiol. Rev. 54: 450-472, 1990.
Steinbuchel, A. and Schlegel, H.G., Mol. Microbiol. 5: 535-542, 1991.
Peoples, O.P. and Sinskey, A.J., J. Biol. Chem. 264: 15293-15297, 1989.
J. Biol. Chem. 264: 15298-15303, 1989.
Slater, S.C., Voige W.H. and Dennis, D.E., J. Bacteriol. 170: 4431-4436, 1988.
Schubert, P., Steinbuchel, A. and Schlegel, H.G., J. Bacteriol. 170: 5837-5847, 1988.
Huisman, G.W., de Leeuw, O., Eggink, G., and Witholt, B. Appl. Environ. Microbiol 54:2924, 1988.
Doi, Y.(ed), In:Microbial polyesters, Chpt.3,and Chpt. 6 VCH Publisher, New York (1990).
Holmes, P.A. In: Developments in crystalline polymers-2 Basset, D. C. (ed), 1-65, 1988.
Gross, R.A., De Mello, C., Lenz, R.W., Brandl, H. and Fuller R.C., Macromolecules 22: 1106, 1989.
Doi, Y. (ed) In: Microbial Polyesters, Chpt.1., VCH Publishers, New York, 1990.
Dawes, E.A. and Senior, P.J., Adv. Microb. Physiol. 10: 135-266 (1973).
Koosha, R., Muller, R.H. and Davis, S.S. In: Critical reviews in therapeutic drug carrier system,6:117-129 (1989).
Poole, R., Science 245: 1187-1189 (1989).
Poirier, Y., Dennis, D.E., Nawrath, C. and Somerville, C. Adv. Mater. 5: 30-36 (1993).
Martin, J.H., Leonard, W.H. and Stamp, D.L. (eds), Chpt 36, In:Principles of Field Crop Prod. 898-932, Macmillan, New York, 1976.
Downey, R.K. and Robbelen, G., In: Oil crops of the world, Robbelen, G., Downey, R.K. and Ashri, A. (eds) Chpt. 16, McGraw-Hill, New York, 1989.
Hiatt, A., Cafferkey, R. and Bowdish, K., Nature 342: 76-78, 1989.
Moffat, A.S., Science 256: 770-771, 1992.
Poirier, Y., Dennis, E., Klomparens, K. and Somerville, C., Science 256: 520-523, 1992.
Poirier, Y., Dennis, D.E., Klomparens, K., Nawrath, C. and Somerville, C., FEMS Microbiol. Lett., 103: 237-246, 1992.
Cashmore, A.R. In: Genetic Engineering of plants (ed. Kosuge, T., Meredith, C.P. and Hollaender, A.) 29-38, Plenum Press NY, 1983.
Peoples, O.P. and Sinskey, A.J., J. Biol. Chem 264: 15298-15303, 1989.
Harwood, J.L., Ann. Rev. Plant Physiol. Plant Mol. Biol. 39: 101-138, 1988.
Preiss, J., Ann. Rev. Plant Physiol. 33: 431-454, 1982.
Keegstra, K. and Olsen, L. J., Annu. Rev. Plant Physiol. Plant Mol. Biol, 40: 471-501, 1989.
Archer, E.K. and Keegstra, K., J. Bioenerg. Biomem., 22: 789-810, 1990.
Robinson, C. and Ellis, R.J., Eur. J. Biochem, 142: 343-346, 1984.
Wasmann, C.C., Reis, R., Bartlett, S.G., and Bohnert, H.J., Mol. Gen. Genet. 205: 446-453, 1986.
Friedmann, A.L. and Keegstra, K., Plant Physiol. 89: 993-999, 1988.
Lubben, T.H., Gatenby, A.A., Ahlquist, P., and Keegstra, K., Plant Mol. Biol. 12: 13-18, 1989.
Schnell, D.J., Blobel, G., and Pain, D., J. Biol. Chem. 266: 3335-3342, 1991.
van de Broeck, G., Timko, M.P., Kausch, A.P., Cashmore, A.R., Van Montagu, M. and Herrera-Estrella, L., Nature 313: 358-363, 1985.
Schreier, P.H., Seftor, E.A., Schell, J., and Bohnert, H.J., EMBO J. 4: 25-32, 1985.
Boutry, M., Nagy, F., Poulsen, C., Aoyagi, K., and Chua N.-H., Nature 328: 340-342, 1987.
Lubben, T.H., and Keegstra, K., Proc. Natl. Acad. Sci 83: 5502-5506, 1986.
Lamppa, G.K., J. Biol. Chem, 263: 14996-14999, 1988.
Gatenby, A.A., Lubben, T.H., Ahlquist, P., and Keegstra, K., EMBO J. 7:1307-1314, 1988.
Cheung, A.Y., Bogorad, L., Van Montagu, M., and Schell, J., Proc. Natl. Acad, Sci. 85: 391-395, 1988.
Lubben, T.H., Theg, S. M. and Keegstra, K., Photosyn. Res. 17: 173-194, 1988.
Benfey, P.N. and Chua, N.-H., Science 250: 959-966, 1990.
Pang, P.P., Pruitt, R.E., and Meyerowitz, E.M., Plant Mol. Biol. 11: 805-820, 1988.
Becker, D., Nucleic Acids Res. 18: 203, 1990.
Bolivar, F. et al., Gene 2: 95-113, 1977.
Pridmore, R.D., Gene 56: 309-312, 1987.
Haughn, G.W., Smith, J., Mazur, B. and Somerville, C.R., Mol. Gen. Genet. 211: 266-271, 1988.
Koncz, C. and Schell, J., Mol. Gen. Genet. 204: 383-396, 1986.
Sambrook, J. Fritsch, E.F. and Maniatis, T. Molecular cloning, a laboratory manual, Cold Spring Harbor Laboratory Press, 1989.
Chang, S.S., Perk, S.K. and Nam, H.-G., Abstract in: Fourth International Conference on Arabidopsis Research, Vienna, 1990.
Senior, P.J. and Dawes, E.A., Biochem. J. 134: 225-238, 1973.
Hanahan, D., J. Mol. Biol. 166: 557-580, 1983.
Rogers, S. C. and Bendich, A.J., Plant Molecular Biology Manual A6: 1-10 (1988).
Feinberg, A.P., and Volgelstein, B., Anal. Biochem. 132, 6-13 (1983).
Poirier, Y., and Jolicoeur, P., J. Virol. 63: 2088-2098 (1989).
Laemmli, Nature 227: 680-685, 1970.
Janes, B., et al. E.A. Dawes (ed.) Novel Biodegradable Microbial Polymers, 175-190 (1990).
Ostle, Anthony G., Applied and Environmental Microbiology, pp. 238-241 (1982).
Kreuz and Kleinig, Eur. J. Biochem. 141, 531-535 (1984).
Schultz, G. & Schulze-Siebert, D. in Biological Role of Plant Lipids, eds. Biacs P.A., Gruiz, K., & Kremmer, T. (Plenum Publ.Corp.,N.Y.,N.Y. pp. 313-319 (1989).
Jorgensen, R. Trends in Biotechnology 8,340-344 (1990).
Fukui,T., et al., Arch. Microbiol. 110, 149-156 (1976).
Haywood, G.W., et al., FEMS Microbiol. Lett 57, 1-6 (1989).
Seymour, G.B., et al., Plant Mol. Biol. 23, 1-9 (1993).
Poirier, Yves, et al., Science, vol. 256 pp. 520-523 (24 Apr. 1992).
International Symposium on Bacterial Polyhydroxy-alkanoates ISBP '92; Gottingen, Jun. 1-5, (1992) L17.
UC Davis-Pacific Rim Food and Agricultural Biotechnology Conference Series-Jun. 20-24 (1992) Genetic Engineering of a Unique Biopolymer Polyhydroxybutyrate.
Poirier, Yves, et al., FEMS Microbiology Reviews 103, 237-246 (1992).
Poirier, Yves, et al., Adv. Mater., 5, No. 1 30-37 (1993).
Proceedings of the Canadian Society of Plant Physiologists, Dec. 13-15, (1992) University of Montreal.
Balter, M., "Plastics: A 21st-Century Crop?", International Herald Tribune (Dec. 15, 1989).
Estelle, M.A. and C. Somerville, "Auxin-resistant Mutants of Arabidopsis thaliana with an Altered Morphology", Mol. Gen. Genet., vol. 206, No. 2, pp. 200-206 (no month identified 1987).
Gerbling, H. and B. Gerhart, "Peroxisomal Degradation of Branched-chain 2-Oxo Acids.sup.1,2 ", Plant Physiol., vol. 91, pp. 1387-1392 (Jul. 1989).
Goodwin, T.W. and E.L. Mercer, "Respiration", In Introduction to Plant Biochemistry, Pergamon Press, Chapter 6, pp. 162-226 (no month identified 1983).
Holmes, P.A., "Applications of PHA - A Microbially Produced Biodegradable Thermoplastic", Phys. Technol., vol. 16, No. 1, pp. 32-36 (no month identified 1985).
Horsch, R., R.T. Fraley, S.G. Rogers, P.R. Sanders, A. Lloyd and N. Hoffmann, "Inheritance of Functional Foreign Genes in Plants", Science, vol. 223, pp. 496-498 (Feb. 1984).
Huisman, G.W., E. Wonink, R. Meima, B. Kazemier, P. Terpstra and B. Witho, "Metabolism of Poly(3-hydroxyalkanoates) (PHAs) by Pseudomonas oleovorans", J. Biol. Chem., vol. 266, No. 4, pp. 2191-2198 (Feb. 1991).
Huisman, G.W., O. de Leeuw, G. Eggink and B. Witholt, "Synthesis of Poly-3-hydroxyalkanoates Is a Common Feature of Fluoresent Pseudomonads", Applied and Environmental Microbiology, vol. 55, No. 8, pp. 1949-1954 (Aug. 1989).
Kung, S.D. and R. Wu, (eds), "Production of Bacillus thuringiensis Insecticidal Proteins in Plants", in Transgenic Plants, vol. 1, pp. 297-315 (no month identified 1993).
Lloyd, A., A.R. Barnason, S.G. Rogers, M.C. Byrne, R.T. Fraley and R.B. Horsch, "Transformation of Arabidopsis thaliana with Agrobacterium tumefaciens", Science, vol. 234, pp. 464-466 (Oct. 1986).
Lundgren, D.G., R.M. Pfister and J.M. Merrick, "Structure of Poly-.beta.-hydroxbutyric Acid Granules", J. Gen. Microbiol., vol. 34, No. 3, pp. 441-446 (May 1964).
Mahler, H.R., "Biological Oxidation of Fatty Acids",
Nawrath Christiane
Poirier Yves
Somerville Christopher R.
Board of Trustees operating Michigan State University
McLeod Ian C.
Rories Charles C. P.
LandOfFree
Processes for producing polyhydroxybutyrate and related polyhydr does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Processes for producing polyhydroxybutyrate and related polyhydr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Processes for producing polyhydroxybutyrate and related polyhydr will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-442608