Processes for producing collagen matrixes and methods of using s

Details Processes for producing collagen matrixes and methods of using s Processes for producing collagen matrixes and methods of using s

1990-12-19

1992-05-05

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424422, 424 852, 424 854, 514801, 530356, 530399, 6048901, A61K 914, A61K 3766, A61K 3712, A61K 3724

Patent

active

051106043

ABSTRACT:
Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves as an effective sustained delivery system for bioactive agents.

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