Processes for producing coenzyme Q10

Details Processes for producing coenzyme Q10 Processes for producing coenzyme Q10

2011-03-22

2011-03-22

Afremova, Vera (Department: 1657)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

C435S041000

Reexamination Certificate

active

07910340

ABSTRACT:
The present invention relates to a process for producing reduced coenzyme Q10which comprises obtaining microbial cells containing reduced coenzyme Q10at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus-produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10which comprises either recovering oxidized coenzyme Q10after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10thereafter. According to the processes of the present invention, reduced coenzyme Q10and oxidized coenzyme Q10can be produced simply on the industrial scale.

REFERENCES:
patent: 3769170 (1973-10-01), Kondo et al.
patent: 4220719 (1980-09-01), Aida et al.
patent: 6156802 (2000-12-01), Mae et al.
patent: 236 552 (1986-11-01), None
patent: 0 051 921 (1982-05-01), None
patent: 0 073 134 (1983-03-01), None
patent: 0 956 854 (1999-11-01), None
patent: 1 123 979 (2001-08-01), None
patent: 1 336 657 (2003-08-01), None
patent: 1 354 957 (2003-10-01), None
patent: 1 386 905 (2004-02-01), None
patent: 1 391 515 (2004-02-01), None
patent: 1 408 024 (2004-04-01), None
patent: 1 415 969 (2004-05-01), None
patent: 1 415 970 (2004-05-01), None
patent: 1 415 971 (2004-05-01), None
patent: 1 415 972 (2004-05-01), None
patent: 1 415 973 (2004-05-01), None
patent: 1 440 962 (2004-07-01), None
patent: 1 452 174 (2004-09-01), None
patent: 930752 (1963-07-01), None
patent: 48-8836 (1973-03-01), None
patent: 54-110388 (1979-08-01), None
patent: 54-119090 (1979-09-01), None
patent: 55-27 (1980-01-01), None
patent: 55-28 (1980-01-01), None
patent: 55-21756 (1980-02-01), None
patent: 55-68295 (1980-05-01), None
patent: 55-148084 (1980-11-01), None
patent: 56-55196 (1981-05-01), None
patent: 56-154994 (1981-11-01), None
patent: 56-154996 (1981-11-01), None
patent: 57-33599 (1982-02-01), None
patent: 57-70834 (1982-05-01), None
patent: 60-75294 (1985-04-01), None
patent: 60-75294 (1985-04-01), None
patent: 10-57072 (1998-03-01), None
patent: 10-109933 (1998-04-01), None
patent: 10-330251 (1998-12-01), None
patent: 2001-61478 (2001-03-01), None
patent: WO 96/17626 (1996-06-01), None
Takada et al. Biochimica et Biophysica Acta. 1982, 679:308-314.
Yoshida et al. “Production of ubiquinone-10 using bacteria”. Journal of General and Applied Microbiology. 1998, 44:19-26.
Disch, Andrea et al., “On the Absence of the Glyceraldehyde 3-Phosphate/Pyruvate Pathway for Isoprenoid Biosynthesis in Fungi and Yeasts,” FEMS Microbiology Letters, vol. 168, No. 2, 1998, pp. 201-208.
Kockova-Kratochvilova, A. et al., “Die Beziehungen innerhalb der GattungCryptococcus(Sanfelice) Vuillemin”,Zbl. Bakt. Abt. II, Bd., vol. 131, No. 7, 1976, pp. 610-631.
Natori, Y. et al., “Production of Coenzyme Q10byPseudomonasN842”,Agric. Biol. Chem., vol. 42, No. 9, 1978, pp. 1799-1800.
Natori, Y. et al., “Enhancement of Coenzyme Q10Accumulation by Mutation and Effects of Medium Components on the Formation of Coenzyme Q Homologs byPseudomonasN842 and Mutants”,Agric. Biol. Chem., vol. 45, No. 10, 1981, pp. 2175-2182.
Ohta, H. et al., “Agromonas oligotrophicagen. nov., sp. nov., a Nitrogen-Fixing Oligotrophic Bacterium”, Antonie van Leeuwenhoek, vol. 49, Nos. 4-5, 1983, pp. 429-446.
Sakato, K. et al., “Agitation-Aeration Studies on Coenzyme Q10Production UsingRhodopseudomonas spheroides,” Biotechnology and Applied Biochemistry, vol. 16, No. 1, 1992, pp. 19-28.
Urakami T., et al., “Production of Isoprenoid Compounds in the Facultative MethylotrophProtomonas extroquens”, J. Ferment. Technol., vol. 66, No. 3, 1988, pp. 323-332.
Urakami, T. et al., “Production of Ubiquinone and Bacteriochlorophyll α byRhodobacter sphaeroidesandRhodobacter sulfidophilus”, Journal of Fermentation and Bioengineering, vol. 76, No. 3, 1993, pp. 191-194.
Urakami, T., et al., “Transfer ofPseudomonas aminovorans(den Dooren de Jong 1926) toAminobactergen. nov. asAminobacter aminovoranscomb. nov. and Description ofAminobacter aganoensissp. nov. andAminobacter niigataensissp. nov.”,International Journal of Systematic Bacteriology, vol. 42, No. 1, Jan. 1992, pp. 84-92.
Venturoli et al.,Biochimica et Biophysica Acta, 935 (1988) pp. 258-272.
Wakabayashi et al.,Biol. Pharm. Bull., 1994, 17(8):997-1002.
Wakao, N. et al., “Acidiphilium multivormsp. nov., an Acidophilic Chemoorganotrophic Bacterium from Pyritic Acid Mine Drainage”,Journal of General and Applied Microbiology, vol. 40, No. 2, 1994, pp. 143-159.
Yabuuchi, E., et al., “Proposals ofSphingomonas paucimobilisgen. nov. and comb. nov.,Sphingomonas parapaucimobilissp. nov.,Sphingomonas yanoikuyaesp. nov.,Sphingomonas adhaesivasp. nov.,Sphingomonas capsulatacomb. nov., and Two Genospecies of the GenusSphingomonas,” Microbiology and Immunology, vol. 34, No. 2, 1990, pp. 99-119.
Yamada, Y., et al., “The Coenzyme Q System in Strains ofTrichosporonSpecies and Related Organisms”,Journal of General and Applied Microbiology, vol. 28, No. 4, 1982, pp. 355-358.
Yoshida, H. et al. “Production of Ubiquinone-10-Using Bacteria”,Journal of General and Applied Microbiology, vol. 44, No. 1, 1998, pp. 19-26.

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