Processes for preparing pyrroles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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10978301

ABSTRACT:
The present invention relates to an improved synthesis of pyrrole capping group precursors.

REFERENCES:
patent: 2004/0018986 (2004-01-01), Pitlik et al.
patent: 2005/0080017 (2005-04-01), Cottrell et al.
Ueda, et al. “A Novel One-Pot Synthesis of Pyrroles From 1, 2, 5-Selenadiazole and 1,3-Diketones” J. Chem. Soc. Perkin Trans. 1, (1994), pp. 2201-2202.
Falk et al. “Selectivity Problem in the Synthesis of Pyrrole” Monatsh. Chem. (1973), 104(4), pp. 925-932.
Fischer et al. “A New Pyrrole Synthesis” Z. Physiol. Chem. (1944), 280, pp. 123-126.
Fischer et al., “A New Synthesis of Pyrroles” Z. Phisiol. Chem. (1948) 282, pp. 152-161.
Cesarino Balsamini et al. “(E)-3-(2-(N-Phenylcarbamoyl)vinyl)pyrrole-2-carboxylic Acid Derivatives. A Novel Class of Glycine Site Antagonists” Journal of Medicinal Chemistry, vol. 41, No. 6, 1998, pp. 808-820.
Matthias Lehr et al. “Synthesis, Biological Evaluation, and Structure-Activity Relationships of 3-Acylindole-2-carboxylic Acids as Inhibitors of the Cytosolic Phospholipase A2” Journal of Medicinal Chemistry. 1997, vol. 40, No. 17, 1997, pp. 2694-2705.

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