Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-07-31
2007-07-31
Saeed, Kamal A. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
10978301
ABSTRACT:
The present invention relates to an improved synthesis of pyrrole capping group precursors.
REFERENCES:
patent: 2004/0018986 (2004-01-01), Pitlik et al.
patent: 2005/0080017 (2005-04-01), Cottrell et al.
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Fischer et al., “A New Synthesis of Pyrroles” Z. Phisiol. Chem. (1948) 282, pp. 152-161.
Cesarino Balsamini et al. “(E)-3-(2-(N-Phenylcarbamoyl)vinyl)pyrrole-2-carboxylic Acid Derivatives. A Novel Class of Glycine Site Antagonists” Journal of Medicinal Chemistry, vol. 41, No. 6, 1998, pp. 808-820.
Matthias Lehr et al. “Synthesis, Biological Evaluation, and Structure-Activity Relationships of 3-Acylindole-2-carboxylic Acids as Inhibitors of the Cytosolic Phospholipase A2” Journal of Medicinal Chemistry. 1997, vol. 40, No. 17, 1997, pp. 2694-2705.
Dixon Lisa A.
Grazier Nyeemah
Kelly Susan C.
Vertex Pharmaceuticals Incorporated
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