Processes for preparing picenadol precursors and novel intermedi

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

546236, 546194, 546281, 546334, 544124, 544360, C07D21122, C07D21102

Patent

active

045814562

ABSTRACT:
The present invention relates to processes for preparing precursors of picenadol, (.+-.)3-(1,3.alpha.-dimethyl-4.alpha.-propyl-4.beta.-piperidinyl)phenol, hydrochloride, a known analgesic. Certain of the compounds prepared by the present process are novel as well.

REFERENCES:
patent: 2845431 (1958-07-01), Lutz et al.
patent: 3177258 (1965-04-01), Rylander et al.
patent: 3946086 (1976-03-01), Gershanov et al.
patent: 4081450 (1978-03-01), Zimmerman
Lieberman et al., in J. Org. Chem. 14, 1001-1012 (1949).
Evans et al., in J. Am. Chem. Soc. 102, 5955-5956 (1980).
Marchand in Chem. Ber. 95, 577-578 (1962).
Schreiber et al., in Angew, Chem. Internat. Edit., vol. 10, No. 5, 330 (1971).
Bryson et al., in J. Org. Chem. 45, 524-525 (1980).
Herbert O. House, "Modern Synthetic Reactions", 2nd edition (1972), pp. 654-655.
K. Blaha et al., Advances in Heterocyclic Chemistry, vol. 6 (1966), p. 219.
Martinez et al., Tetrahedron, vol. 34 (1978), pp. 3027-3036.
Beeken et al., J. Org. Chem., vol. 45 (1980), pp. 1336-1338.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Processes for preparing picenadol precursors and novel intermedi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Processes for preparing picenadol precursors and novel intermedi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Processes for preparing picenadol precursors and novel intermedi will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2067155

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.