Processes for preparing novel squalene synthetase inhibitors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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4352541, 435911, C12P 1718, C12N 114, C12R 1645

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active

052504247

ABSTRACT:
This invention relates to strains of the species Curvularia lunata isolated from tree bark and useful in a fermentation process to form compounds of formula (I): ##STR1##

REFERENCES:
patent: 5026554 (1991-06-01), Bartizal et al.
patent: 5053425 (1991-10-01), Bartizal et al.
patent: 5055487 (1991-10-01), Bartizal et al.
Database WPIL Week 6800, Derwent Pub. Ltd., London, GB, AN 66-23017F and NL-6 603 344 (Syntex Corp.). (1966).
ATCC Catalogue of Fungi/Yeasts, 17th Edition, p. 128, (1987).

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