Processes for preparing cholesterol lowering compounds

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435913, 4352561, C12P 1706, C12R 166

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active

052447952

ABSTRACT:
This invention relates to processes employing cultures which are useful for preparing compounds of structural formula (I). ##STR1##

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K. Fukuyama, J. C. S. Perkin II, 683-686 (1978).
M. S. Brown and J. L. Goldstein, Science, 232: 34-47 (1986).
P. T. S. Ma et al., Proc. Natl. Acad. Sci. USA, 83: 8370-8374 (1986).
W. J. McGahren et al., J. Amer. Chem. Soc., 96: 1616-1617 (1974).
W. J. McGahren et al., J. Org. Chem., 41: 66-71 (1976).
K. Fukuyama et al., Tetrahedron Lett., 3: 189-190 (1976).
J. L. Goldstein and M. S. Brown, Nature, 343: 425-430 (1990).

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