Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1988-12-07
1990-05-01
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
562466, C07C 5948, C07C 5964
Patent
active
049220101
ABSTRACT:
There are disclosed a process for preparing 2-hydroxy-2-(6-methoxy-2-naphthyl)propionic acid or 2-hydroxy-(4-substituted phenyl)propionic acid derivative which comprises reacting 2-methoxynaphthalene or substituted benzene derivatives with pyruvic acid in the presence of a Lewis acid and then, if necessary, hydrolyzing the obtained product, and a process for preparing 2-(6-methoxy-2-naphthyl)propionic acid or 2-(4-substituted phenyl)propionic acid derivative which comprises reducing 2-hydroxy-2-(6-methoxy-2-naphthyl)propionic acid or 2-hydroxy-2-(4-substituted phenyl)propionic acid derivative in a lower aliphatic acid in the presence of an inorganic acid under hydrogen atmosphere by using a metal catalyst.
Ishikawa Hideo
Kashima Mikito
Kashiwagi Kouichi
Noda Yumiki
Killos Paul J.
Ube Industries Ltd.
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