Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid

Details Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid

2011-04-26

2011-04-26

Desai, Anand U (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

C435S227000, C536S023100, C536S023200

Reexamination Certificate

active

07932064

ABSTRACT:
The invention provides novel processes for making ethyl-4-cyano-3-hydroxybutyrate, e.g., (R)-ethyl 4-cyano-3-hydroxybutyric acid, and 4-cyano-3-hydroxybutyric acid. The invention provides protocols for making and 4-cyano-3-hydroxybutyric acid and ethyl-4-cyano-3-hydroxybutyrate by whole cell processes, cell lysate processes, “one pot processes” and “multi-pot” processes using a variety of parameters.

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