Processes and intermediates for preparing macrocycles

Details Processes and intermediates for preparing macrocycles Processes and intermediates for preparing macrocycles

1994-12-05

1997-04-15

Chang, Ceila

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 20, C07D40506

Patent

active

056211082

ABSTRACT:
Novel processes for the preparation of lactam- and lactone-containing macrocyles are provided. In preferred embodiments, rapamycin and demethoxyrapamycin are prepared by a convergent synthesis regime. Intermediates useful in the synthetic processes are also provided.

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