Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.

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530333, 530338, C07K 110, C07K 508

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active

051342251

ABSTRACT:
Immunoregulatory N-(S-3-alkyl-4-heptenoyl)- and N-(S-3-alkylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine and esters thereof are synthesized via R-trans-2-hexen-4-ols, R-3-alkyl-4-heptenoic acid and S-3-alkylheptanoic acid.

REFERENCES:
patent: 3985722 (1976-10-01), Yoshida et al.
patent: 4045475 (1977-08-01), Chan et al.
patent: 4113968 (1978-09-01), Mori et al.
patent: 4374264 (1983-02-01), McGarry
patent: 4401658 (1983-08-01), Bouchaudon et al.
patent: 4565653 (1986-01-01), Ives et al.
patent: 4767743 (1988-08-01), Rizzi
Morrison et al. Organic Chemistry. 1959, p. 126.
Paulson et al. Organic Chemistry. 1980, pp. 1025-1031.
Herberman et al., eds. 13th International Congress of Chemotherapy. 1983. pp. 203/19-203/35.
Basic Principles of Organic Chemistry, John D. Roberts et al., p. xiii, (1964).
Greenwood, J. Org. Chem., v. 27, pp. 2308-2311, (1962).
Carruthers, "Some Modern Methods of Organic Synthesis", 2nd ed., Cambridge University Press, Cambridge, pp. 106-107, 340-341 (1978).
House, "Modern Synthetic Reactions", 2nd ed., Benjamin, Inc., Menlo Park, CA, pp. 263, 269, 274, 275 (1972).
Chemical Abstracts, v. 101, abstract 6924e; abstracting Vig et al., Indian J. Chem., Sect. B, v. 22B, pp. 1126-1128 (1983).
Katsuki et al. J. Am. Chem. Soc., v. 102, pp. 5974-5976 (1980).
Sharpless et al., Pure Appl. Chem., v. 55, pp. 589-604 (1983).
Midland et al., J. Org. Chem, v. 50, pp. 1143-1144 (1985).
Midland et al., Tetrahedron, v. 40, pp. 1371-1380 (1984).
Kondo et al., in ACS Symposium Series-Synthetic Pyrethroids (1976), pp. 128-136.
Crombie et al., J. Chem. Soc., pp. 869-875 (1952).

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