Processes and intermediates for making 16-phenoxy and 16-substit

Details Processes and intermediates for making 16-phenoxy and 16-substit Processes and intermediates for making 16-phenoxy and 16-substit

1985-09-13

1988-10-25

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560121, C07C 1700

Patent

active

047805625

ABSTRACT:
This invention relates to a process for making a compound of formula I ##STR1## in the form of a stereoisomer or mixture thereof, wherein R is hydrogen, lower alkyl; X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy, and the wavy lines represent the .alpha. or .beta. configuration with the proviso that when one wavy line is .alpha. the other is .beta., or a pharmaceutically acceptable, non-toxic salt of the compound wherein R is hydrogen; novel intermediates useful for preparing these compounds; processes for making the intermediates; and a stereoisomer of the compound of formula I wherein R is methyl and X is hydrogen and a process for making same.

REFERENCES:
patent: 4578505 (1986-03-01), Collins

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