Processes and intermediate compounds for the preparation of plat

Details Processes and intermediate compounds for the preparation of plat Processes and intermediate compounds for the preparation of plat

1995-01-12

1998-10-06

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

530330, 530333, 530339, C07K 750, C07K 110

Patent

active

058177493

ABSTRACT:
This invention provides processes for the synthesis of platelet glycoprotein IIb/IIIa inhibitors and intermediate compounds useful in said processes. The compounds afforded by this invention have the formula: ##STR1##

REFERENCES:
patent: 5192746 (1993-03-01), Lobl et al.
patent: 5322931 (1994-06-01), Hubbs et al.
patent: 5384309 (1995-01-01), Barker et al.
Miller, A.E. and Bischoff, J.J., "Facile Conversion of Amino Acids to Guanidino Acids", Journal of Synthetic Organic Chemistry, 1986 No. 9, 777-779.
Eberhard Schroder and Klaus Lubke, "The Synthesis of Cyclis peptides", The Peptides, 1965, vol. I, 271-272.

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