Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1995-08-08
1997-02-18
Le, Hoa Van
Drug, bio-affecting and body treating compositions
Dentifrices
424 48, 424 52, 424 57, 222 94, 222129, 222478, 222482, A61K 716
Patent
active
056039220
ABSTRACT:
The present invention relates to remineralization, without demineralization, by applying to the teeth a composition which is present in either one or in two phases and which does not react to any large extent until introduced into the oral cavity and upon such introduction does not rapidly precipitate. One phase systems contain at least one water-soluble calcium compound, at least one other water-soluble, non-toxic compound containing a divalent metal different from calcium, and at least one water-soluble inorganic phosphate compound. If desired at least one water-soluble fluorine compound may be added to the system. In two phase systems one phase contains the calcium and the divalent metal compounds and the other the phosphate and optionally, the fluoride compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent, but controlled, reaction causes rehardening of demineralized areas in the dental enamel.
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International Application Publication WO94/18938, Sep. 1, 1994.
Usen Norman
Winston Anthony E.
Enamelon Inc.
Le Hoa Van
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