Processed vascular endothelial growth factor-B polypeptides

Details Processed vascular endothelial growth factor-B polypeptides Processed vascular endothelial growth factor-B polypeptides

2004-09-24

2008-03-11

Allen, Marianne P. (Department: 1647)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S350000, C530S399000

Reexamination Certificate

active

07341996

ABSTRACT:
VEGF-B polypeptides from the PDGF family of growth factors having the property of promoting mitosis and proliferation of vascular endothelial cells, DNA sequences encoding these polypeptides, pharmaceutical compositions containing them and antibodies which react with them. The VEGF-B polypeptides are useful in stimulating angiogenesis as well as in diagnostic applications.

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Orlandini et al., “Identification of a c-fos-Induced Gene That is Related to the Platelet-Derived Growth Factor/Vascular Endothelial Growth Factor Family”, Proc. Natl. Acad. Sci. USA, vol. 93, pp. 11675-11680 (1996).

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