Process to produce anthracycline glycosides

Details Process to produce anthracycline glycosides Process to produce anthracycline glycosides

1981-10-19

1983-05-10

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435886, C12P 1956, C12R 1465

Patent

active

043830374

ABSTRACT:
There is presented a process for producing anthracycline glycosides A by converting the sugar moiety of anthracycline glycosides B, represented by the following formula: ##STR1## into the sugar moiety of anthracycline glycosides A, represented by the following formula: ##STR2## with the aid of a microorganism belonging to the species Streptomyces galilaeus or Streptomyces melanogenes.

REFERENCES:
patent: 4329339 (1982-05-01), Fujiwara et al.
Journal of Antibiotics, vol. 32, pp. 472-481, (May 1979).
Umezawa et al, The Journal of Antibiotics, (Japan), vol. 28, No. 10, pp. 830-835, (Oct. 1975).

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