Process to prepare oxazolidinones

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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Reexamination Certificate

active

07087784

ABSTRACT:
The present invention relates to a one-step process to prepare pharmacologically active 2-oxo-5-oxazolidinylmethylacetamides.

REFERENCES:
patent: 5688792 (1997-11-01), Barbachyn
patent: 5883093 (1999-03-01), Hutchinson
patent: 5952324 (1999-09-01), Barbachyn
patent: 5968962 (1999-10-01), Thomas
patent: 6107519 (2000-08-01), Pearlman
patent: WO 97/37980 (1997-10-01), None
patent: WO 99/24393 (1999-05-01), None
patent: WO 01/98297 (2001-12-01), None
JR Gage, et al., “Sterodivergent synthesis of sulfoxide-containing oxazolidinone antibiotics,” Tetrahedron Letters, 41 (2000), pp. 4301-4305.
MA Mbappe, et al., “Enzymatic Resolutions in 3-amino-1,2-propanedial series,” Tetrahedron: Asymmetry, 4(5), pp. 1035-1040, 1993.
SE Schaus and Eric N. Jacobsen, “Dyanamic Kinetic Resolution of Epichlorohydren via Enantioselective Catalytic Ring Opening with TMSN,. Practical Synthesis of Aryl Oxazolidinone Antibacterial Agents,” Tetrahedron Letters. vol. 37, No. 44, pp. 7937-7940, 1996.

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