Process to prepare metastasis-inhibitory factor

Details Process to prepare metastasis-inhibitory factor Process to prepare metastasis-inhibitory factor

1990-05-22

1992-06-30

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Hemic or immune system

A61K 3512, A61K 3528

Patent

active

051261480

ABSTRACT:
Human hematopoietic cells produce metastasis-inhibitory factor (MIF). MIF exhibits a remarkable metastasis-inhibitory activity on viral diseases and immunopathies, as well as on malignant tumors. The MIF-producing human hematopoietic cells are easily proliferative by in vitro tissue culture and in vivo proliferation using a non-human warm-blooded animal. T cells exhibit a high MIF producibility. Mitogens augment the production of MIF when used as an MIF inducer.

REFERENCES:
Gould Medical Dictionary, 4th ed., McGraw-Hill Book Company, 1979, p. 160.

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