Process to make magnetically responsive fluorescent polymer part

Details Process to make magnetically responsive fluorescent polymer part Process to make magnetically responsive fluorescent polymer part

1989-12-14

1994-02-01

Lusignan, Michael

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

427128, 427131, 427214, 427222, A01N 102

Patent

active

052830799

ABSTRACT:
This invention provides a novel process of producing magnetically responsive fluorescent polymer particles comprising polymeric core particles coated evenly with a layer of polymer containing magnetically responsive metal oxide. A wide variety of polymeric particles with sizes ranging from 1 to 100 microns can be used a core particles and transformed into magnetically responsive polymer particles. The surface of these magnetically responsive polymer particles can be coated further with another layer of functionalized polymer. These magnetically responsive fluorescent polymer particles can be used for passive or covalent coupling of biological material such as antigens, antibodies, enzymes or DNA/RNA hybridization and used as solid phase for various types of immunoassays, DNA/RNA hybridization probes assays, affinity purification, cell separation and other medical, diagnostic, and industrial applications.

REFERENCES:
patent: 4177253 (1979-12-01), Davies et al.
patent: 4490436 (1984-12-01), Kawakami et al.
patent: 4628037 (1986-12-01), Chagnon et al.

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