Process to make HIV protease inhibitor from (2S)-4-picolyl-2-pip

Details Process to make HIV protease inhibitor from (2S)-4-picolyl-2-pip Process to make HIV protease inhibitor from (2S)-4-picolyl-2-pip

1995-03-15

1997-04-08

McKane, Joseph

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D40106

Patent

active

056189370

ABSTRACT:
A process for making a clinically efficacious HIV protease inhibitor eliminates one step in its synthesis, by an alternative convergent synthesis using 2(S)-4-picolyl-2-piperazine-t-butylcarboxamide as an intermediate.

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