Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1995-09-19
1998-04-28
Ketter, James
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
530358, 536 231, C12N 1564, A61K 3816, C07H 2100
Patent
active
057443351
ABSTRACT:
The present invention provides a process of transfecting a cell with a polynucleotide mixed with one or more amphipathic compounds and an effective amount of a DNA-binding protein. Exemplary and preferred DNA-binding proteins are H1, H2A, and H2B. Exemplary and preferred amphipathic compounds are cationic amphipathic compounds.
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Budker Vladimir
Fritz Jeffery
Hagstrom James
Wolff Jon A.
Brusca John S.
Johnson Mark K.
Ketter James
Mirus Corporation
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