Process of selectively blocking amino functions in aminoglycosid

Details Process of selectively blocking amino functions in aminoglycosid Process of selectively blocking amino functions in aminoglycosid

1976-06-17

1979-01-23

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

260429J, 2604381, 260439R, 536 4, 536 17, C07H 1522, C07H 2300

Patent

active

041362543

ABSTRACT:
Selective blocking of some amino groups in a polyamino organic compound having at least one pair of available neighboring hydroxyl and amino groups is effected by first preparing in situ transition metal salt complexes of available neighboring amino and hydroxyl group pairs in said polyamino organic compound, followed by introduction of blocking groups on the non-complexed amino groups and, finally, removing the transition metal cations from the selectively N-blocked polyamino organic compound complex to obtain a polyamino organic compound having selectively blocked amino groups.
This process is particularly valuable when carrying out aminocyclitol-aminoglycoside transformations utilizing transition metal salt complexes of cupric acetate, nickel (II) acetate, cobalt (II) acetate or mixtures thereof.

REFERENCES:
patent: 3388141 (1968-06-01), Berenbaum
patent: 3682995 (1972-08-01), Ogden
patent: 3786079 (1974-01-01), Yonezawa
patent: 3787464 (1974-01-01), Neri et al.
patent: 3872080 (1975-03-01), Daniels
patent: 3878193 (1975-04-01), Reimann
patent: 3925353 (1975-12-01), Umezawa et al.

Affiliated with

Also associated with

Rating

Process of selectively blocking amino functions in aminoglycosid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process of selectively blocking amino functions in aminoglycosid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process of selectively blocking amino functions in aminoglycosid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2273966