Process of producing a sustained release preparation containing

Details Process of producing a sustained release preparation containing Process of producing a sustained release preparation containing

1984-06-26

1987-03-24

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

424 19, 424 22, A61K 922, A61K 926, A61K 952

Patent

active

046524428

ABSTRACT:
In a process of producing a sustained release preparation containing indomethacin or niomethacin, the active ingredient in the form of a powder as well as one or more food grade substances having a solubility of at least 1 gram per 10 milliliters in an aqueous liquid at any pH value from 1 to 9 and a temperature of 37.degree. C., and one or more food grade substances having a solubility of at least 1 gram per 100 milliliters in an aqueous liquid at any pH value from 1 to 9 and a temperature of 37.degree. C. are thoroughly mixed and the resulting mixture is mixed with a solution of one or more food grade substances which in an aqueous liquid have

REFERENCES:
patent: 4173626 (1979-11-01), Dempski et al.
patent: 4525345 (1985-06-01), Dunn et al.
Lachman et al., The Theory and Practice of Industrial Pharmacy, Lea & Febiger.

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