Process of producing 3-trehalosamine by fermentation

Details Process of producing 3-trehalosamine by fermentation Process of producing 3-trehalosamine by fermentation

1980-10-09

1982-01-12

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C12P 1926

Patent

active

043106277

ABSTRACT:
Novel antibiotic 3-trehalosamine (U-59,834) producible in a fermentation under controlled conditions using the new microorganism Nocardiopsis trehalosei sp. nov., NRRL 12026.
This antibiotic is active against Gram-positive bacteria, for example, Staphylococcus aureus, Bacillus subtilis, and Diplococcus pneumoniae. Thus, 3-trehalosamine can be used in various environments to eradicate or control such bacteria.
Antibiotic 3-trehalosamine can be shown by the following structural formula: ##STR1##

REFERENCES:
patent: 4212944 (1980-07-01), Celmer et al.
Hough et al., "J.C.S. Perkin I", 1973, pp. 287-290.
Naganawa et al., "J. Antibiotics", vol. 27, pp. 145-146, 1974.
Wright et al., "J. Chem. Soc. Chem. Commun.", 1977, pp. 710-712.

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