Process of preparing cephalosporanic acid ester derivatives

Details Process of preparing cephalosporanic acid ester derivatives Process of preparing cephalosporanic acid ester derivatives

1974-03-08

1976-04-27

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D50104

Patent

active

039534375

ABSTRACT:
A process of preparing a .DELTA..sup.3 -cephalosporanic acid ester derivative which comrises reacting a cephalosporanic acid sulfoxide ester derivative with thionyl halide or a phosphorous halide.
The compounds prepared by the process of this invention are useful as intermediate compounds for preparing cephalosporin antibiotics and the compounds themselves are also potential antibacterials.

REFERENCES:
patent: 2237866 (1941-04-01), Guinot
patent: 3641014 (1972-02-01), Murphy
patent: 3660395 (1972-05-01), Wright
patent: 3660396 (1972-05-01), Wright

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