Process of preparation of collagen containing in major proportio

Details Process of preparation of collagen containing in major proportio Process of preparation of collagen containing in major proportio

1992-11-06

1994-07-19

Lee, Lester L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Scleroproteins, e.g., fibroin, elastin, silk, etc.

43524025, 43524026, 435174, 435176, C08L 8906, A61L 1504, A61K 922

Patent

active

053310926

ABSTRACT:
A process of preparation of collagen containing in major proportion insoluble collagen is disclosed, including rinsing and washing the collagenic tissue, acidifying the ground material pH value 1 to 4 to get a collagenic paste which is diluted in a diluting solution to get the collagen gel having a concentration in collagen lower than about 2.5 by weight expressed in dry collagen, and performing a shearing stirring at high speed producing ultrasonic effect to get a substantially homogeneous collagenic gel. The collagen has improved mechanical resistance and thermal stability.

REFERENCES:
patent: 4280954 (1981-07-01), Yannas et al.
patent: 4863856 (1989-09-01), Dean, Jr. et al.

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