Chemistry: electrical current producing apparatus – product – and – Fuel cell – subcombination thereof – or method of making or... – Fuel cell with solid electrolyte
Reexamination Certificate
2001-01-23
2003-04-01
Page, Thurman K. (Department: 1615)
Chemistry: electrical current producing apparatus, product, and
Fuel cell, subcombination thereof, or method of making or...
Fuel cell with solid electrolyte
C424S725000, C424S725100
Reexamination Certificate
active
06541163
ABSTRACT:
FIELD OF THE INVENTION
The present invention relates to a method for preparing a medicated bath powder, specifically to a method of processing a medicated bath powder from natural herb medicated bath liquid.
BACKGROUND OF THE INVENTION
There has been nearly a thousand year history of using Tibetan medicated bath liquor (TMBL) made by crude Tibet medicine, in China, to treat various diseases such as rheumatoid arthritis, rheumatic arthritis, psoriasis, postpartum convulsions, muscular atrophy, callosity, hemiplegia and hypertension. The therapeutic effects are remarkable and no obvious toxic actions or side effects are exhibited. Sources for the Tibetan medicines are plentiful and each of them have individual distinguishing features and are specialized for the treatment of difficult and complicated cases in Tibetan medical therapy.
The characteristics of the above-mentioned diseases are that they are chronic diseases which are hard to cure. Both ordinary Chinese Traditional therapy and Western medicine require long therapeutic courses for the treatment of these diseases, and the therapeutic effects are still not ideal. However, if these diseases are treated with from one to three courses of Tibetan medicine bath liquor, much improved therapeutic results are achieved. Recently a number of, “Sections of TMBL”, have been established in many places in Tibet, Xinjiang, Inter Mongolia, Gansu, Qinghai, Sichuan and Henan. However, these hospitals are related to the source of the Tibetan medicines and most of them are set up in remote mountainous areas and county towns where limited access brings about much inconvenience for patients. Medicated bath therapy requires the patients to be away from wind in the spring and autumn and to be treated under conditions of constant heat. For these reasons, if under the direction of a physician, the patients can be treated and nursed at home or in a nearby hospital or clinic, the advantages of the therapy and medical care can be received with reduced difficulty and expense for the patient. In view of the above-mentioned facts, the dosage-forms of TMBL should be improved in order to offer MBL therapy to a greater number of patients.
In a paper by Jiuxi Jabu, “Observation of Therapeutic Effects of Tibetan Medicated Bath Liquor in 50 Cases of Rheumatoid Disease”, in the Chinese Journal of Folk Medicine 1997, Vol. 3, No. 3, p. 18, it is reported that a bath liquor containing traditional pharmaceuticals, so called “Sweet Dew Bath with five flavor”, was prepared with five kinds of traditional drugs, namely
Junipers clavaum
L., Rhododendron,
Myricaria germanica
(L.) Desv. Chinese Ephedra and Artemisia (wormwood). Its specific preparative method is as follows.
The above-mentioned five kinds of Chinese traditional medicines are collected. After cutting them into slices and then drying, distillers yeast is added for fermentation and they are air dried again. Several other kinds of traditional medicines may also be added, depending on the patient's condition and severity of the disease. The above-resulting mixture is put into a white cloth bag, soaked with water overnight and decocted. After the contents in the pot are concentrated to a half volume, the decocted liquor is poured into a vat and the drug bag is decocted once again into ⅓ of the original volume, and the decocted medicine liquid mixture is poured into the vat again. Decoction is repeated again to a volume of ⅓ of the original volume. The liquid from three decoctions is combined and mixed homogeneously with highland barley resulting in ready to use MBL.
Due to the fact that the volume of the medicated liquid is large and the time for production is long, even if such MBL could be obtained by industrial production, it would be difficult for patients to use at home. Hence, patients must be treated during hospitalization. Therefore, improvements in the dosage-form of the medicated bath liquor (MBL) are needed.
In the First Colloquium on Chinese Tibetan Drugs and Their Naturally Developing Strategy (Papers Collection, pp. 23-31), Li Fu-Yin Et al., there are reported preparative methods of TMBL. According to the article, a crude traditional medicine is selected, washed, cut into slices (5-10 mm), which are then put into a multi-functional extracting jar. Water is added in an amount of 10 times by weight of the total quantity of the crude medicine. Extraction under heat proceeds for one hour. Both volatile oil and a distillate containing volatile oil are filtered to obtain the 1st extract. Water is added to the drug residue in an amount 6 times the total volume of the crude medicine. Again, extraction proceeds under heat for another one hour and the liquid is then filtered to obtain the 2nd extract. Water is then added to the drug residue in an amount 4 times the total volume of the crude medicine. Extraction under heat proceeds for half an hour and the liquid is then filtered to obtain the 3rd extract. The three portions of extract are combined and concentrated under reduced pressure to form a paste extract. The latter is mixed homogeneously with volatile oil as well as a distillate containing volatile oil. A suitable stabilizer is added, along with auxiliary bath liquid, to the mixture which gives an ointment containing 2 g of crude medicine/ml, which can be diluted to form MBL. Although the advantage of this ointment formulation is that it decreases the volume, the water content of such an ointment is still more than 60%. This volume is too large and it renders transportation and application inconvenient. Besides, a certain amount of stabilizer is added which results in an increased amount of chemical constituents rendering the product more susceptible to mold. The above-mentioned drawbacks limit the development and practical application of TMBL therapy.
Because of the deficiencies of the liquid and ointment forms of MBL, studies on other dosage forms have been reported. For example, in Otkan Qimo et al. “An Exploration for Application and Improvement of Preparative Method of Mongolian Medicated Bath” in the Chinese Journal of National Medicine 1997, Vol. 3, No. 1, p. 29, a method for preparing a bath powder was disclosed. First of all, a number of crude medicines, which are not suitable for extraction, such as aromatic medicines, mineral medicines and animal medicines, etc., are selected and crushed. A series of botanical medicines, such as
Junipers clavaum
L., Artemisia (wormwood), Chinese Ephedra,
Myricaria germanica
(L.) Desv.
Rhododendron anthopogonoides
leaves are decocted and readied for use. First, the crude medicines are decocted for 2 hours (drug:water=1:5 by weight). The filtrates are collected and the residue is again decocted for 6 hours. Filtration and decoction are repeated 4-5 times until the medicine liquid is colorless and tasteless. Several batches of the medicine are combined and concentrated by heating. A paste is formed and laid out to cool. The crushed crude medicines, which are not suitable for boiling with water, are added. Then a powered substance is formed by stirring, baking and grinding. When used to treat a particular disease, 150-250 g (one dose per every person) of suitable medicine bath powder are mixed with water, stirred homogeneously and boiled. For use, it is put into a bathtub containing a suitable amount of warm water and is then stirred homogeneously. The advantages of the medicated bath powder are that it significantly decreases the weight and volume of the medicine needed so that it is more convenient to transport and use. However, the disadvantages are that the effective constituents could be destroyed during baking and the effective volatile constituents will volatilize to a certain degree and lose their effect. In addition, the crushed crude medicines, which are added during the last step of formulating, are boiled with water during use, which may not sufficiently release the effective constituents from the medicine.
DISCLOSURE OF THE INVENTION
The present invention provides a medicated bath powder that overcomes the draw
Fubara Blessing
Page Thurman K.
Thorpe North and Western LLP
Tibet Yutuo Institute of Tibetan Medicine
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