Process of manufacture of biodegradable microcapsules having wal

Details Process of manufacture of biodegradable microcapsules having wal Process of manufacture of biodegradable microcapsules having wal

1994-10-25

1997-04-22

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

264 4, 264 43, 264 432, 424499, 426 98, 426534, 514963, B01J 1316, A61K 952

Patent

active

056226560

ABSTRACT:
The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules.
According to the invention, the microcapsules comprise a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, the proportion of polyholosides, for example glycosaminoglycans, relative to the atelocollagen preferably being between 18 and 50% by weight. These microcapsules can be manufactured either by a process involving interfacial crosslinking or by the extrusion of a laminar flow which is broken up by vibrations into individual droplets, which fall into a crosslinking bath.
These microcapsules are biocompatible by virtue of the presence of atelocollagen, which has most of the advantageous properties of collagen, namely a very low antigenicity and a perfect biodegradability. The are therefore particularly suitable for the manufacture of cosmetic, pharmaceutical or food compositions.

REFERENCES:
patent: 3423489 (1969-01-01), Arens et al.
patent: 4280954 (1981-07-01), Yannas et al.
patent: 4378017 (1983-03-01), Kosugi et al.
patent: 4391909 (1983-07-01), Lim
patent: 4426337 (1984-01-01), Suzuki et al.
patent: 4711783 (1987-12-01), Huc et al.
patent: 4780321 (1988-10-01), Levy et al.
patent: 4925677 (1990-05-01), Feijen
patent: 4931546 (1990-06-01), Tardy et al.
patent: 5011692 (1991-04-01), Fujioka
patent: 5169631 (1992-12-01), Rase
patent: 5385738 (1995-01-01), Yamahira et al.
patent: 5395620 (1995-03-01), Huc et al.
"Utilising Collagen in Drug Formulation", Manufacturing Chemist. vol. 57, No. 9, Sep. 1986, pp. 64-65, 67, London, Great Britain.
"Alkohol, Glykosaminoglykane, Kollagen: Neue Anwendungen in der Kosmetik", Seifen, Ole, Fette, Wachse, vol. III, No. 1, Jan. 1985, pp. 14-16, Augsburg, Germany.

Affiliated with

Also associated with

Rating

Process of manufacture of biodegradable microcapsules having wal does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process of manufacture of biodegradable microcapsules having wal, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process of manufacture of biodegradable microcapsules having wal will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-339402