Process of making polymeric hydrogels by reactive extrusion

Details Process of making polymeric hydrogels by reactive extrusion Process of making polymeric hydrogels by reactive extrusion

2006-10-17

2006-10-17

Nutter, Nathan M. (Department: 1711)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

C525S252000, C525S253000

Reexamination Certificate

active

07122602

ABSTRACT:
What is described is a reactive extrusion process of making a polymeric hydrogel of a polymeric anhydride or acid, e.g. maleic anhydride or maleic acid polymer, or copolymer thereof, crosslinked with a crosslinking agent containing at least 2 crosslinkable groups, particularly, —OH or —NH2, or both. The reaction product is a crosslinked polymeric ester or amide/imide, or both, suitably having a mole ratio of —OH, or —NH2, to —COOH, of 1:10 to 10:1, preferably 2:10 to 7:1. The hydrogel is particularly swellable in water, e.g. >100% in 1 hour in aqueous media; and forms a thin, tacky layer on a substrate, which property is useful in bioadhesive products.

REFERENCES:
patent: 5635568 (1997-06-01), Plochocka et al.
patent: 6583225 (2003-06-01), Plochocka et al.
patent: 6706817 (2004-03-01), Plochocka et al.

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