Process of making penicillamine

Details Process of making penicillamine Process of making penicillamine

1975-12-19

1977-11-29

Helfin, Bernard

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603067C, 2603067R, C07C 9910

Patent

active

040605485

ABSTRACT:
Penicillamine and its hydrochloride are made by reacting i-butyraldehyde with elemental sulfur or a sulfur-containing compound and with gaseous ammonia so as to form 2-isopropyl-5.5-dimethyl-thiazoline-.DELTA..sup.3, then reacting the latter compound with substantially anhydrous hydrogen cyanide so as to form the corresponding thiazolidine 4-carbonitrile, thereupon treating the latter compound with an excess of concentrated hydrochloric acid at an elevated temperature and separating the components of the mixture formed and recovering the penicillamine hydrochloride which may then be converted to the free D,L-penicillamine.

REFERENCES:
patent: 3948984 (1976-04-01), Osinger et al.

Affiliated with

Also associated with

Rating

Process of making penicillamine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process of making penicillamine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process of making penicillamine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1633554