Process of making chiral 2-aryl-1,4-butanediamine derivatives as

Details Process of making chiral 2-aryl-1,4-butanediamine derivatives as Process of making chiral 2-aryl-1,4-butanediamine derivatives as

1992-09-30

1995-02-21

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562490, 562495, 562840, 562887, 544334, 544335, 544336, 544264, 546147, 546174, 546341, 548201, 548206, 548240, 5483415, 5483094, 5483761, 548491, 549 71, 549 58, 549469, 549470, 549499, 564161, C07C 5940

Patent

active

053918193

ABSTRACT:
Disclosed herein is a process of making chiral 2-aryl-1,4-butanediamine derivatives useful as neurokinin-A antagonists of Formula 7 ##STR1##

REFERENCES:
patent: 4904656 (1990-02-01), Weissmuller et al.
CA 110(5), 38874r 1988.
Biochem. and Phy. Res. Comm. vol. 184, No. 3, (1992).
Beckwith, et al., Aust. J. Chem., 1992, 45, 289-308.

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