Process of immunoassay of a substance in a liquid sample contain

Chemistry: analytical and immunological testing – Thyroid hormone tests

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436512, 436520, 436533, 436534, 436817, 436818, 436825, G01N 33546, G01N 33555, G01N 33563

Patent

active

047255560

ABSTRACT:
A process of immunoassay of a selected substance in a liquid sample containing one or more other non-selected substances, each of these substances being comprised of at least two structurally different chains, the process comprising among others addition of a dissociating agent, such as for example a proteolytic enzyme, to the sample, mixing of the so-obtained liquid, inactivation of the dissociating agent, addition of antiserums, and determination of the amount of this selected substance in the liquid sample.

REFERENCES:
patent: 4256629 (1981-03-01), Bahl
patent: 4397960 (1983-08-01), Moussebois et al.
patent: 4459359 (1984-06-01), Neurath
Masson, U.S. Application Serial No. 747,174, filed 6/1985.
"Structure of an Exophthalmos-producing Factor Derived from Thyrotropin by Partial Pepsin Digestion", by L. D. Kohn and R. J. Winand, The Journal of Biological Chemistry, No. 16, pp. 6503-6508, 1975.

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