Process of extracting and purifying biologically effective ingre

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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514 1, A01N 6500, A61K 3578

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active

059103078

ABSTRACT:
This invention to a process of extracting and purifying biologically effective ingredients from combined medicinal plants and their plant extract composition and more particularly, to a process for effective extracting and purifying the biologically effective ingredients by mixing Clematis Radix, Trichosanthes root and Prunella Herba in a certain ratio, being useful for alleviating acute/chronic inflammation and also for inhibiting platelet/whole blood aggregation, abnormally proliferated immunocytes (e.g., B-lymphocyte, T-lymphocyte), inflammation-inducing enzymes (5-Lipoxygenase, Cyclooxygenase-I, Cyclooxygenase-II) and also scavenging activity on toxic active oxygen species when compared to a single plant extracts, together with their extract composition, which may be effectively used as an anti-inflammatory agent with analgesic effects, rheumatoid arthritis drug and agents for improving peripheral blood circulation.

REFERENCES:
Research Archives of Useful Plants Resources in Korea, Korea Research Institute of Chemical Technology, pp. 780-781 (1988). (with English translation of relevant parts).
An Explanatory Diagram of Korean Medicinal Plants, Youngrim Pub., pp. 489-490 (1990). (with English translation of relevant parts).
Research Archives of Useful Plants Resouces in Korea, Korea Research Institute of Chemical Technology, pp. 354-357 (1988). (with English translation of relevant parts).
An Explanatory Diagram of Korean Medicinal Plants, Youngrim Pub., pp. 960-963 (1990). (with English translation of relevant parts).
Research Archives of Useful Plants Resouces in Korea, Korea Research Institute of Chemical Technology, pp. 480-482 (1988). (with English translation of relevant parts).
Chemical Research for Prunella Herba, Lee Jak-pyung et al., Bulletin of Medical College in Beijing, 17 (4), pp. 297-299 (1985). (with English translation of relevant parts).
Dong-Eui-Bo-gam, Hyangyak Gibsung-bang and Kwangjee Beakub (3 excerpts from conventional herbal books). (with English translation of relevant parts).
Journal of Pharm. Phamacol., 44 (5), pp. 456-458 (1992).
Chung-Kuo-Li-Hsueh-Pao, 10 (4), pp. 381-384 (1989). (with English Abstract).
Biochem. Pharmac., 29, pp. 533-538 (1980).
Agents Actions, 17, pp. 375-376 (1985).

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