Process of enhancing immmunogenic response in mammals by the adm

Details Process of enhancing immmunogenic response in mammals by the adm Process of enhancing immmunogenic response in mammals by the adm

1977-09-06

1982-04-06

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424 92, 536 18, 536 53, A61K 3170, C07H 506

Patent

active

043235611

ABSTRACT:
A process is described for enhancing the immunogenic response of mammals. N-acylated-D-glucosamines were administered parenterally in the form of liposomes to mice at or before the time of administration of an immunogen or radiation, with the result that comparable or superior enhancement of the immune response was observed for these glycolipids when compared to LPS in assays measuring anti-SRBC or HGG hemagglutinin titers. The radiation protective effect of some of the synthetic adjuvants gave a definite protection, with up to 40% of lethally irradiated mice (700 R) surviving.

REFERENCES:
patent: 3697652 (1972-10-01), Rovati et al.
patent: 3934009 (1976-01-01), Gey et al.

Affiliated with

Also associated with

Rating

Process of enhancing immmunogenic response in mammals by the adm does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process of enhancing immmunogenic response in mammals by the adm, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process of enhancing immmunogenic response in mammals by the adm will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-592352