Process intermediate for the preparation of encainide

Details Process intermediate for the preparation of encainide Process intermediate for the preparation of encainide

1987-04-20

1989-01-24

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21302

Patent

active

048002267

ABSTRACT:
A novel dimethylsulfate quaternary salt process intermediate useful in the manufacture of the antiarrhythmic agent encainide.

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Dykstra and Minielli, J. Med. Chem., 16, 1015-1020 (1973).
Byrne et al., J. Pharmacology and Experimental Therapeutics, 200, 147-154 (1977).
Horwitz, Journal of Organic Chemistry, 21, 1039-1041 (1956).
Stanek et al., Chem. Abstracts, 49, 314h (1955).
Phillips, Journal of Organic Chemistry, 12, 333-341 (1947).

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