Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Reexamination Certificate
2004-03-08
2008-10-21
Burkhart, Michael (Department: 1633)
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
C435S005000, C435S320100
Reexamination Certificate
active
07439051
ABSTRACT:
The present invention relates to compositions and methods for the selection and use of surface exposed epitopes. The present invention includes in vivo and in vitro phage peptide diplay methods for the identification and selection of peptides and peptide associated factors with desired properties (e.g., targeting specificity, stability, etc.). The present invention further provides methods and compositions for the isolation and identification of peptide-specific antibodies. The present invention also includes methods and compositions employing nuclear localization signals for enhanced nuclear transport and expression of DNA.
REFERENCES:
patent: 5766905 (1998-06-01), Studier et al.
patent: 5811093 (1998-09-01), Merril et al.
patent: 6184370 (2001-02-01), Layton et al.
patent: 6495662 (2002-12-01), Gardella et al.
patent: 6872519 (2005-03-01), Sokoloff et al.
Merril CR, Biwas B, Carlton R, Jensen NC, Creed GJ, Zullo S, Adhya S, Long circulating bacteriophage as antibacterial agents, 1996, Proc Natl Acd Sci USA 93: 3188-3192.
Sahu A, Kay BK, Lambris JD, Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library, 1996, J Immunol 157: 884-891.
Novagen 1997 Catalog, pp. 24-26.
GenBank entry for T7 phage minor capsid protein 10B, Accession # NP-041997, May 4, 2006.
T7 Select System Manual, Novagen, 2002.
Condron, B. et al., “Frameshifting in Gene 10 of Bacteriophage T7”, 1991, J. Bacteriol., vol. 173: pp. 6998-7003.
GenBank entry for lambda phage major capsid protein D, Accession # P03712, May 16, 2006.
Sokoloff Alexander V.
Wolff Jon A.
Burkhart Michael
Ekena Kirk
Johnson Mark K.
Mirus Bio Corporation
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