Process for using the yeast ADH II promoter system for the produ

Details Process for using the yeast ADH II promoter system for the produ Process for using the yeast ADH II promoter system for the produ

1996-11-27

1999-02-02

Guzo, David

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 694, 435 696, 43525421, C12P 2100, C12P 2102, C12N 119

Patent

active

058663711

ABSTRACT:
The invention relates to a novel process for using the yeast ADH II promoter system for the production of heterologous proteins in high yields, for example for preparing hirudins, miniproinsulins, leptins or derivatives thereof.

REFERENCES:
patent: 4668662 (1987-05-01), Tripier
patent: 4791100 (1988-12-01), Kramer et al.
patent: 5180668 (1993-01-01), Crause et al.
patent: 5422249 (1995-06-01), Liersch et al.
Zhang, Yiying et al., "Positional cloning of the mouse obese gene and its human homologue," Nature, vol. 372, pp. 425-432, (Dec. 1, 1994).
Hersbach, George J. M. et al., "Biotechnology of Industrial Antibiotics," Drugs and the Pharmaceutical Sciences, vol. 22, pp. 45-140 (1984).
Dodt, Johannes et al., "The Complete Covalent Structure of Hirudin," Biol. Chem. Hoppe-Seyler, vol. 366, pp. 379-385 (Apr. 1985).
Markwardt, F., "Pharmacology of Hirudin: One hundred years after the first report of the anticoagulant agent in medicinal leeches," Biomed. Biochim. Acta, vol. 44, pp. 1007-1013 (1985).
Irani, Meher et al., "Transcription of the ADH2 Gene in Saccharomyces cerevisiae Is Limited by Positive Factors That Bind Competitively to Its Intact Promoter Region on Multicopy Plasmids," Molecular and Cellular Biology, pp. 1233-1241 (Mar. 1987).
Price, Virginia L. et al., "Expression of Heterologous Proteins in Saccharomyces cerevisiae Using the ADH2 Promoter," Methods in Enzymology, vol. 185, pp. 308-318 (1990).
Tottrup, Hanne V. et al., "A Process for the Production of Human Proinsulin in Saccharomyces cerevisiae," Biotechnology and Bioengineering, vol. 35, pp. 339-348 (1990).
Romanos et al., Yeast, vol. 8, pp. 423-488, 1992.

Affiliated with

Also associated with

Rating

Process for using the yeast ADH II promoter system for the produ does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for using the yeast ADH II promoter system for the produ, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for using the yeast ADH II promoter system for the produ will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1116378