Surgery – Blood drawn and replaced or treated and returned to body
Patent
1985-06-24
1987-01-06
Phynes, Lucille M.
Surgery
Blood drawn and replaced or treated and returned to body
210612, 210615, 210927, 424 85, 424 88, 424 95, 424105, 435174, 435175, 435176, 435177, 435178, 435179, 435180, 435181, 435883, 604 5, 604 6, A61M 3700
Patent
active
046344179
ABSTRACT:
A process for removing immunosuppressive substances from the blood serum of cancer patients comprises contacting the serum at a temperature below room temperature and preferably not greater than 5.degree. C., with Protein A of S. aureus immobilized on a substrate. Conducting the immunoabsorption at low temperature reduces the amount of anaphylatoxins produced in the process and thereby reduces the side effects of immunoperfusion treatment. An apparatus for low-temperature immunoperfusion treatment comprises a chamber for containing the immunoabsorbent, inlet and outlet tubes connected to the chamber, and a cooling jacket surrounding the chamber and at least a portion of the inlet tube.
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Georgetown University
Phynes Lucille M.
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