Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-03
1996-11-19
Weddington, Kevin E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3135
Patent
active
055763464
ABSTRACT:
A process and pharmaceutical composition for treatment of uremic pruritus in humans is disclosed. The pharmaceutical composition comprises of a chromone compound of the following formula, or a pharmacologically acceptable salt, ester or amide thereof: ##STR1## dissolved or dispersed in a pharmacologically acceptable carrier. In accordance with the process, a therapeutically effective amount of the composition is topically administered to a pruritic lesion of a human patient.
REFERENCES:
patent: 4271182 (1981-06-01), Sullivan
patent: 4362742 (1982-12-01), Sullivan
Chemical Abstracts, vol. 87, No. 26, "Topical Compositions for Skin Diseases", Brit. 1,475,503 (1978).
Habif, T. P., ed., Clinical Dermatology: A Color Guide to Diagnosis and Therapy, 2nd Ed., The C. V. Mosby Co. (St. Louis MO: 1989) pp. 582-585.
Brauenwald, et al., eds., Harrison's Principles of Internal Medicine, 11th Ed., McGraw-Hill Book Co. (New York: 1990), pp. 3043, 1161, and 1958.
Ahmed Mumtaz
Anaebonam Aloysius O.
Clemente Emmett
Mendes Robert W.
Ascent Pharmaceuticals, Inc.
Weddington Kevin E.
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