Process for total synthesis of pladienolide B and...

Details Process for total synthesis of pladienolide B and... Process for total synthesis of pladienolide B and...

2006-10-13

2010-10-19

Desai, Rita J (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S625000

Reexamination Certificate

active

07816401

ABSTRACT:
A process for producing a compound represented by Formula (11):wherein P1, P7, P8, P9and R1are the same as defined herein, characterized by including reacting a compound represented by Formula (12):with a compound represented by Formula (13):in the presence of a catalyst.

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Kanada et al., “Total Synthesis of the Potent Antitumor Macrolides Pladiendolide B and D”, Chemlnform, vol. 38, Issue 40, Oct. 2, 2007, pp. 4350-4355.

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