Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1977-04-13
1980-11-25
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
26039745, 424309, 424311, 424330, 424301, 424329, 424252, 424308, 424324, 424274, 424251, 424267, 424279, A61K 31705, C07J 4100
Patent
active
042358876
ABSTRACT:
This invention relates to a new method of therapy comprising the administration of a pro-drug to a human or animal, said pro-drug being a compound formed by a therapeutic compound chemically combined with another moiety by a photocleavable bond and irradiating the diseased area with ultraviolet radiation in an amount sufficient to cleave the bond and release the therapeutic compound in a therapeutically effective amount. Specifically disclosed are pro-drugs which are cleaved to therapeutically active medications which are anti-proliferative and anti-inflammatory compounds and the treatment of inflammatory and/or proliferative skin diseases therewith.
REFERENCES:
patent: 4069322 (1978-01-01), Bodor et al.
Voorhees John J.
Wierenga Wendell
Jiles Henry R.
Killinger John J.
The Upjohn Company
Whittenbaugh Robert C.
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