Process for their preparation of .beta.-lactam antibacterial age

Details Process for their preparation of .beta.-lactam antibacterial age Process for their preparation of .beta.-lactam antibacterial age

1979-11-07

1981-09-22

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, 424271, 260239A, C07D49900

Patent

active

042909481

ABSTRACT:
A process for the preparation of the compounds of the formula (II): ##STR1## and salts and cleavable esters thereof wherein R.sub.1 is a hydrocarbon group of up to 12 carbon atoms and which optionally also contain up to 4 heteratoms selected from oxygen, nitrogen, sulphur or chlorine and bromine which process comprises the reaction of a cleavable ester of a compound of the formula (III): ##STR2## with one equivalent of a strong base of low nucleophilicity and thereafter with a compound of the formula (IV) or (V):

REFERENCES:
patent: 4155912 (1979-05-01), Menarp et al.

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