Process for the whole broth extraction of avermectin

Details Process for the whole broth extraction of avermectin Process for the whole broth extraction of avermectin

1981-12-21

1983-12-27

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 168, 536 71, 536 185, C07H 108

Patent

active

044232110

ABSTRACT:
A process for the whole broth extraction of avermectins wherein the pH of the whole broth is adjusted with mineral acid and then contacted with a solvent extractant so that the avermectic active component is taken up by the solvent. The now avermectin rich extractant is then processed through a solvent concentration step and the avermectin isolated by conventional crystallization. The extractant is then recycled with appropriate make-up to extract a subsequent batch of whole broth.

REFERENCES:
patent: 4160083 (1979-07-01), Cole et al.
patent: 4160084 (1979-07-01), Miller et al.
patent: 4160861 (1979-07-01), Cole et al.
patent: 4161583 (1979-07-01), Wilson et al.
patent: 4172940 (1979-10-01), Chaiet
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4285963 (1981-08-01), Arison et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.

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