Process for the treatment of diseases caused by oxidative stress

Details Process for the treatment of diseases caused by oxidative stress Process for the treatment of diseases caused by oxidative stress

1987-05-12

1988-07-12

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 3133

Patent

active

047570636

ABSTRACT:
The invention is related to a process for the treatment of diseases caused by oxidative stress in human beings comprising administering to said human being a pharmaceutical preparation comprising 2-phenyl-1,2-benzisoselenazol-3(2H)-one as active agent in an amount of 10 to 2000 mg per day.

REFERENCES:
patent: 4352799 (1982-10-01), Renson et al.
R. Weber et al., Bulletin de la Soc. Chim. de France 1976 (7/8) pp. 1124-1126.
H. Sies, Oxidative Stress, 1985, pp. 1-8.
R. C. Allen et al., Biochemical and Biophysical Research Communications, vol. 47, No. 4, pp. 679-684 (1972).
Knox Van Dyke et al., Microchemical Journal 25, 514-523 (1980).
David A. Hume et al., Biochem. J. (1981) vol. 198, pp. 661-667.Enrique Cadenas et al., Biochem. J. (1980) vol. 192, pp. 303-309.
Alberto Boeris et al., Federation Proceedings, vol. 40, No. 2, (1981) pp. 195-198.
Robert C. Young et al., The New England Journal of Medicine, vol. 305, No. 3, (1981), pp. 139-153.
Thomas R. Tritton et al., Science, vol. 217, (1982), pp. 248-250.
Albrecht Wendel, Methods in Enzymology, vol. 77, (1981), pp. 325-333.

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