Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1981-06-22
1983-03-01
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D21379
Patent
active
043755453
ABSTRACT:
6-Aminonicotinic acid is reacted with an alkali carbonate selected from the group consisting of sodium carbonate and potassium carbonate. The reaction is carried out at elevated temperature and in dimethylformamide. The 6-aminonicotinic acid alkali salt so produced is reacted with 3-chloromethylpyridine hydrochloride. The reaction is carried out at elevated temperature and in dimethylformamide. The desired nicotinyl ester is thus produced.
REFERENCES:
patent: 4031104 (1977-06-01), Bossert et al.
Luber, Jr. Edward J.
Somerville William A.
Warner, Jr. Paul L.
Zusi F. Christopher
Jiles Henry R.
Simon Morton S.
Westwood Pharmaceuticals Inc.
Whittenbaugh Robert C.
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