Process for the synthesis of solifenacin

Details Process for the synthesis of solifenacin Process for the synthesis of solifenacin

2008-03-28

2010-06-22

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07741489

ABSTRACT:
The present invention provides an improved synthetic strategy for the preparation of solifenacin and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 6017927 (2000-01-01), Takeuchi et al.
patent: 1714965 (2006-10-01), None
patent: 1757604 (2007-02-01), None
Naito et al., Journal of Medicinal Chemistry (2005), 48(21), 6597-6606.
U.S. Appl. No. 12/515,689, filed Aug. 4, 2009, Jordi Puig.
Naito et al., Synthesis and Antimuscarinic Properties of Quinuclidin-3-yl 1,2,3,4-Tetrahydroisoquinoline-2-carboxylate Derivatives as Novel Muscarinic Receptor Antagonists,J. Med. Chem.(2005) 48, 6597-6606.

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