Process for the synthesis of organic compounds

Details Process for the synthesis of organic compounds Process for the synthesis of organic compounds

2011-08-30

2011-08-30

Saeed, Kamal (Department: 1622)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C568S938000

Reexamination Certificate

active

08008504

ABSTRACT:
The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is a key intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):

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Tokunaga, Teruhisa, et al: “Oxindole derivatives as orally active potent growth hormone secretagogues”, J. Med. Chem. vol. 44, pp. 4641-4649 (2001).
Sun et al: “Preparation of pyrimidine derivatives as protein kinase inhibitors”, Database accession No. 2006:65549, abstract, 2006.

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